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Why Clinical Trial Protocols Are the Real Bottlenecks—Not the Sites, Not the Staff

Why Clinical Trial Protocols Are the Real Bottlenecks—Not the Sites, Not the Staff

How bloated protocol design is the silent killer of trial success (and why no one wants to admit it)

Rudy Malle's avatar
Rudy Malle
Apr 15, 2025
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Clinical Research Space
Clinical Research Space
Why Clinical Trial Protocols Are the Real Bottlenecks—Not the Sites, Not the Staff
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a woman sitting at a table with lots of papers
Photo by Dimitri Karastelev on Unsplash

Let’s cut to the chase.

We’ve spent years pointing fingers at sites.
“Too slow.”
“Not enough patients.”
“Staff turnover is killing timelines.”
“Training compliance is a mess.”

But what if we’ve been blaming the wrong people all along?

Because the real problem…
Is upstream.
It’s not the site.
It’s not the CRC who just quit.
It…

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